Antioxidant Capacities of Flavones and Benefits in Oxidative-Stress Related Diseases

Oxidative Stress Related Diseases in Newborns

We review oxidative stress-related newborn disease and the mechanism of oxidative damage. In addition, we outline diagnostic and therapeutic strategies and future directions. Many reports have defined oxidative stress as an imbalance between an enhanced reactive oxygen/nitrogen species and the lack of protective ability of antioxidants. From that point of view, free radical-induced damage cause...

oxidative stress and benefits of antioxidant agents in acute and chronic hepatitis

Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Diabetic Retinopathy

Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes and is the leading cause of blindness in young adults. Oxidative stress has been implicated as a critical cause of DR. Metabolic abnormalities induced by high-glucose levels are involved in the development of DR and appear to be influenced by oxidative stress. The imbalance between reactive oxygen specie...

Antioxidant targeting by deferiprone in diseases related to oxidative damage.

The design of antioxidant pharmaceuticals is a major challenge for the treatment of many clinical conditions and in aging. Free radical damage (FRD) is primarily catalysed by iron catalytic centers. Most of the natural and synthetic antioxidants are ineffective in inhibiting FRD because of the achievement of low concentrations at the affected tissues. Despite that many chelators inhibit FRD in ...

Antioxidant Effect of Terminalia Chebula Aqueous Extract on Age-Related Oxidative Stress in Heart

Reactive oxygen species (ROS) are generated by normal metabolic processes or from exogenous insults and chemical agents. They are capable of damaging essential biomolecules and accelerating cancer, cardiovascular diseases and neurodegenerative diseases. In the present study, the antioxidant role of Terminalia chebula aqueous extract was evaluated against age-related oxidative stress in heart ...